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Omecamtiv mecarbil
CAS No. 873697-71-3
Omecamtiv mecarbil ( CK-1827452 )
Catalog No. M16353 CAS No. 873697-71-3
Omecamtiv mecarbil (CK-1827452) is the first potent cardiac myosin activator that can specifically activate the cardiac myosin S1 domain but not other muscle myosins.
Purity : >98%(HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 43 | In Stock |
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| 5MG | 69 | In Stock |
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| 10MG | 113 | In Stock |
|
| 25MG | 186 | In Stock |
|
| 50MG | 332 | In Stock |
|
| 100MG | 494 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameOmecamtiv mecarbil
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NoteResearch use only, not for human use.
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Brief DescriptionOmecamtiv mecarbil (CK-1827452) is the first potent cardiac myosin activator that can specifically activate the cardiac myosin S1 domain but not other muscle myosins.
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DescriptionOmecamtiv mecarbil (CK-1827452) is the first potent cardiac myosin activator that can specifically activate the cardiac myosin S1 domain but not other muscle myosins. In clinical trials, omecamtiv mecarbil has been considered as a promising therapeutic approach to treat systolic heart failure1.
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SynonymsCK-1827452
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PathwayEndocrinology/Hormones
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TargetATPase
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RecptorATPase
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Research AreaCardiovascular Disease
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Indication——
Chemical Information
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CAS Number873697-71-3
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Formula Weight401.43
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Molecular FormulaC20H24FN5O3
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Purity>98%(HPLC)
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SolubilityEthanol: 6 mg/mL (14.94 mM); DMSO: 80 mg/mL (199.28 mM)
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SMILESO=C(N1CCN(CC2=CC=CC(NC(NC3=CC=C(C)N=C3)=O)=C2F)CC1)OC
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Chemical Namemethyl 4-(2-fluoro-3-(3-(6-methylpyridin-3-yl)ureido)benzyl)piperazine-1-carboxylate
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Anderson RL, et al. Mol Bio Cell, 2005, 16.
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